Jobs in Cambridge

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

This role involves leading drug discovery programs using AI-driven computational chemistry, either as a Program Lead or Computational Chemistry Lead. You'll shape Isomorphic Labs' AI platform by integrating cutting-edge machine learning into cheminformatics workflows, guide projects from hit identification to candidate selection, and collaborate across disciplines. The position emphasizes scientific leadership, technical innovation, and mentorship within a culture focused on transforming drug discovery through AI.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Associate Director, Clinical Program Management, Cambridge, MA

The Clinical Program Manager will lead the transition of internal drug programs from pre-IND stages into clinical trial execution, managing timelines, budgets, and cross-functional teams. This role involves close collaboration with AI/ML and data science teams, CROs, and global stakeholders to ensure efficient, high-probability clinical development. The position operates in a hybrid model, requiring in-office presence multiple days per week in Cambridge, MA.

Isomorphic Labs England

Hybrid Permanent

Senior Security Researcher

This role involves researching emerging threats in generative AI systems, including prompt injection, poisoning, and extraction attacks. The candidate will investigate attacker tradecraft, provide actionable feedback on product performance, and collaborate with machine learning and product teams. Work includes both rapid prototyping and open-ended research to enhance AI-driven cyber resilience.

Darktrace London, UB8 1LQ, United Kingdom

Hybrid Permanent

Senior C++ Software Engineer

Design and develop high-performance, low-latency C++ systems for cybersecurity applications, focusing on innovation, memory safety, and scalability. Work within a cross-functional R&D team to build secure, production-grade native tooling that defends against unknown threats. Utilise modern C++ (C++17/20+), systems programming, and performance optimisation in Linux and cloud environments.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Hybrid Permanent

Medical Director, Clinical Development (Oncology), Cambridge, MA

Lead clinical development strategy for oncology programs, translating AI-driven insights into actionable trial designs and overseeing medical monitoring from discovery through to clinical proof-of-concept. Serve as the primary medical liaison with regulatory authorities, investigators, and cross-functional teams, ensuring scientific rigor, patient safety, and compliance with global standards.

Isomorphic Labs England

Hybrid Permanent

Director, Translational Medicine, Oncology, Cambridge, MA

Lead the development and execution of translational medicine strategies for oncology programs, integrating AI-driven insights to advance drug discovery from preclinical to clinical stages. Serve as a cancer biology expert, guiding biomarker and companion diagnostic development while collaborating across multidisciplinary teams. Shape clinical trial design and regulatory submissions with a focus on mechanism of action, drug resistance, and novel therapeutic combinations.

Isomorphic Labs Cambridge, United Kingdom

Software Engineer (Python)

Develop and prototype innovative cybersecurity solutions as part of a cross-functional R&D team, focusing on advancing Darktrace’s AI-driven threat detection capabilities. Work on projects spanning rapid prototyping to structured development of core platform features, using Python and containerized environments. Collaborate with engineers, designers, and strategists to enhance the speed, scale, and intelligence of cyber resilience systems.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Senior Software Engineer (C++ & Swift)

You will develop and maintain the macOS codebase using modern C++ and Swift, contributing to the design and implementation of innovative cybersecurity solutions. The role involves rapid prototyping, structured development of platforms, and mentoring team members. You will work closely with cross-functional teams, participate in code reviews, and help advance Darktrace’s AI-driven methodology for detecting and responding to unknown cyber threats.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Threat Research Analyst

The role involves in-depth analysis of cyber threats, malware, and adversary TTPs using data science and analytical techniques. You'll proactively hunt for emerging threats, develop detection methodologies, produce threat intelligence reports, and collaborate with research and product teams. The position emphasizes turning complex data into actionable insights and contributing to public-facing research and conferences.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Product Manager - NDR

This role involves shaping the Network Detection and Response (NDR) product within Darktrace’s AI-driven cybersecurity platform. The Product Manager will bridge customer needs, technical development, and go-to-market strategy, working closely with R&D, marketing, and sales teams. Key responsibilities include defining product direction, validating features, and ensuring effective internal and external communication of product capabilities.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Hybrid Permanent

Product Manager - NDR

This role involves shaping the direction of Darktrace's Network Detection and Response (NDR) product by aligning customer needs with technical development. The Product Manager will work closely with R&D, marketing, and go-to-market teams to prioritise features, ensure effective product messaging, and support customer adoption. A strong understanding of cybersecurity, particularly in network security and real-world NDR deployment, is essential for success in this position.

Darktrace London, UB8 1LQ, United Kingdom

Hybrid Permanent

Director of Product

Lead product strategy and execution within Darktrace's Platform Services division, driving customer value through AI-powered cybersecurity solutions. You'll manage a team of product professionals, shape cross-functional roadmaps with engineering and UX, and influence senior stakeholders to elevate product practices. The role combines hands-on product leadership with strategic influence in a fast-paced, innovative environment.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Hybrid Permanent

Machine Learning Researcher

Conducts machine learning research to advance Darktrace's AI-driven cybersecurity platform, prototyping new models and integrating them into production systems. Works across research, engineering, and security teams to solve novel problems using language models, neural networks, and statistical methods. Focuses on developing optimised, deployable ML solutions for diverse environments including edge devices.

Darktrace Cambridge, CB2 3BJ, United Kingdom