Latest Isomorphic Labs Jobs

Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA

This role involves leading translational biology strategies in oncology and immunology, bridging AI-driven drug design with experimental validation. You will design in vivo pharmacology studies, develop biomarker strategies, and manage CRO partnerships to generate robust data for clinical translation. The position plays a key role in advancing drug candidates from discovery through to clinical development by integrating biological insights with machine learning predictions.

Isomorphic Labs England

Hybrid Permanent

Senior Technical Program Manager (InfoSec), London

This role involves translating the company's information security strategy into actionable engineering initiatives, managing complex security projects across cloud infrastructure, identity access management, and secure software development. The person will act as a bridge between security and engineering teams, ensuring robust protection of AI models and sensitive drug discovery data while maintaining research velocity. Key responsibilities include building automated dashboards for risk visibility, securing emerging AI workflows, and navigating the Google/Alphabet ecosystem.

Isomorphic Labs London, United Kingdom

On-site Permanent

Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA

Lead or contribute to drug discovery projects by integrating medicinal chemistry expertise with AI-driven platforms. Collaborate closely with machine learning teams to refine predictive models and drive programs from hit identification to candidate selection. Play a key role in shaping next-generation drug design through innovation in structure-based and fragment-based approaches, while mentoring teams and managing external research partners.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

This role involves leading drug discovery programs using AI-driven computational chemistry, either as a Program Lead or Computational Chemistry Lead. You'll shape Isomorphic Labs' AI platform by integrating cutting-edge machine learning into cheminformatics workflows, guide projects from hit identification to candidate selection, and collaborate across disciplines. The position emphasizes scientific leadership, technical innovation, and mentorship within a culture focused on transforming drug discovery through AI.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Director, Translational Medicine, Oncology, Cambridge, MA

Lead the development and execution of translational medicine strategies for oncology programs, integrating AI-driven insights to advance drug discovery from preclinical to clinical stages. Serve as a cancer biology expert, guiding biomarker and companion diagnostic development while collaborating across multidisciplinary teams. Shape clinical trial design and regulatory submissions with a focus on mechanism of action, drug resistance, and novel therapeutic combinations.

Isomorphic Labs Cambridge, United Kingdom

Research Leader (DMPK), Cambridge, MA

Leads DMPK strategy in drug discovery projects, integrating AI-first approaches to optimize ADME and toxicology models. Designs screening cascades and interprets DMPK, PD, and safety data to guide candidate selection. Collaborates with chemistry, pharmacology, and AI teams to advance molecules from hit identification to clinical development.

Isomorphic Labs Cambridge, United Kingdom

Executive Assistant, London

Provide high-level administrative support to senior leadership by managing complex calendars, coordinating cross-functional initiatives, and ensuring seamless logistics for meetings and events. Act as a trusted point of contact, handling confidential communications and driving operational efficiency across a fast-paced, interdisciplinary AI-driven drug discovery environment. The role demands proactive problem-solving, discretion, and the ability to adapt quickly in a hybrid working model.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Research Leader (Toxicology), Cambridge, MA

Lead toxicology strategy for drug discovery projects using an AI-first approach, guiding safety assessment from early discovery to regulatory submission. Develop predictive toxicology models in collaboration with machine learning teams and external CROs. Mentor team members and contribute to reducing animal testing through innovative, data-driven methodologies.

Isomorphic Labs Cambridge, United Kingdom

Research Engineer (LLM Performance), London

You will work on optimizing large language models for performance and scalability within a cutting-edge AI-driven drug discovery environment. The role involves implementing post-training methods, diagnosing bottlenecks in distributed systems, and deploying low-precision techniques to support real-world drug design applications. Collaboration with interdisciplinary research teams is central to translating novel AI methods into production-ready systems.

Isomorphic Labs London, United Kingdom

Bioinformatics Engineer, London

Build and maintain high-fidelity biological data pipelines that integrate public and internal datasets into a standardized, version-controlled foundation for AI-driven drug discovery. Collaborate with machine learning, computational biology, and chemistry teams to enable robust model training and accelerate therapeutic development through scalable, production-grade bioinformatics infrastructure.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Head of Medicinal Chemistry, Drug Design, London

Lead a team of 25 medicinal chemists redefining drug discovery by integrating AI into molecular design. Provide strategic oversight, mentor chemists, and collaborate with AI and biology teams to accelerate projects toward clinical candidate nomination. Shape workflows, challenge traditional approaches, and drive innovation in a culture of scientific excellence and continuous learning.

Isomorphic Labs London, United Kingdom

On-site Permanent

ML Research Engineer, London

Develop and optimise cutting-edge AI models at the intersection of machine learning and drug discovery, translating research into scalable, production-ready systems. Work closely with scientists to build predictive and generative models using advanced deep learning techniques, with a focus on innovation in computational biology and chemistry. Contribute to a collaborative, interdisciplinary team advancing a digital biology platform for transformative medicine development.

Isomorphic Labs London, United Kingdom

On-site Permanent

Research Scientist (Applied LLMs), London

A Research Scientist will focus on applying Large Language Models to drug discovery challenges, developing novel ML techniques and models that integrate with biological and chemical data. The role involves close collaboration with interdisciplinary teams of scientists and engineers to advance AI-driven drug design. Work includes model development, experimentation, and scaling frameworks for predictive applications in a fast-paced research environment.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Research Scientist (Machine Learning), London

A Research Scientist in machine learning will develop novel deep learning models and algorithms to accelerate drug discovery, working in an interdisciplinary team of scientists and engineers. The role involves designing architectures, training models, and applying ML to complex biological and chemical problems, with opportunities to lead projects and mentor others depending on experience.

Isomorphic Labs London, United Kingdom

Hybrid Permanent

Software Engineer (TechOps), London

Design and manage cloud infrastructure for a cutting-edge AI-driven drug discovery platform, supporting research and production workloads on GCP. Work closely with scientists, ML researchers, and engineers to build scalable, secure, and automated systems using Kubernetes, Terraform, and modern DevOps practices. Operate in a hybrid environment with a focus on innovation and scientific impact.

Isomorphic Labs United Kingdom

Hybrid Permanent