Latest High Performance Computing Jobs

Spotlight

Director of Technology - AI

Lead the AI technology strategy and R&D portfolio at Digital Catapult, shaping the future of AI through collaborative research with academia and industry. Drive innovation in emerging areas like agentic AI and AI assurance, while mentoring technical teams and influencing national policy. The role combines strategic leadership with hands-on engagement in technology translation and horizon scanning across the UK’s deep tech ecosystem.

Digital Catapult Bristol, County Of Bristol, United Kingdom £110,000 – £130,000 pa

Hybrid Permanent

Spotlight

Senior Machine Learning Scientist

This role involves developing and deploying custom machine learning and LLM-powered systems for customer feedback analysis, including fine-tuning, retrieval, summarisation, and agentic workflows. The scientist will lead experimentation, evaluation, and productionisation of models while mentoring team members and integrating cutting-edge AI research into real-world applications.

Chattermill London, United Kingdom

Remote Permanent

High Performance Computer Scientist /HPC Developer

This role involves designing and optimising large-scale high-performance computing (HPC) systems, focusing on improving computational efficiency, reliability, and scalability. You'll work closely with engineers and researchers to solve complex infrastructure challenges involving distributed systems, parallel processing, and performance-critical workloads. The position demands deep technical expertise across hardware, operating systems, and low-level optimisation.

IT Graduate Recruitment London, United Kingdom £50,000 pa

Hybrid Permanent

Senior HPC Performance Engineer

As a Senior HPC Performance Engineer, you will conduct in-depth performance analysis on large multi-GPU and multi-node clusters, evaluate proof-of-concepts, and triage performance issues. You will collaborate with a dynamic team across multiple time zones to advance NVIDIA's communication libraries and optimize HPC and DL applications.

NVIDIA £221,250 – £507,000 pa

Remote Permanent

Senior HPC Performance Engineer

As a member of our team in NVIDIA's NVHPC compilers & tools group, you will analyze and run High Performance Computing (HPC) applications on HPC servers and systems to gain insight into the performance characteristics of these applications. The applications...

NVIDIA

Software Engineer, GPU Infrastructure- ChatGPT Engineering

Design and build software to manage large-scale GPU infrastructure supporting ChatGPT inference, including automation, observability, and capacity planning. Develop internal platforms and AI-powered agents to improve fleet efficiency and reduce manual operations across thousands of GPUs. Collaborate with research and engineering teams to enhance reliability and utilization of compute resources.

OpenAI London, United Kingdom

Hybrid Permanent

Junior Software Engineer - Imaging Systems

Develop and maintain C++ software for advanced imaging systems, focusing on high-speed data processing and hardware/software integration. Work within a multidisciplinary R&D team to build performance-critical backend applications and tools for scientific and industrial applications. Contribute to system architecture, debugging, and product development in a technically demanding environment.

Marcus Webb Associates Limited Hollington, East Sussex, East Sussex, TN37 7BA, United Kingdom £35,000 – £40,000 pa

On-site Permanent

Staff Hardware Verification Engineer

This role involves working on cutting-edge SoC and interconnect IP verification, influencing verification strategies, and developing verification components like BFMs, monitors, and testbenches. You will collaborate with global engineering teams and contribute to advanced semiconductor technologies used in automotive, AI, cloud, and high-performance computing.

MicroTech Consulting Krakow, United Kingdom £160,000 – £260,000 pa

On-site Permanent

Design Verification Engineer

This role involves developing and executing simulation-based verification for a Register Bank compiler, building Python-based validation flows, and enhancing CI pipelines. You will work on advanced SoC assembly and register generation flows, influencing verification and tooling in a highly technical EDA environment.

MicroTech Consulting Krakow, United Kingdom

On-site Permanent

Staff Machine Learning Software Engineer, Research

This role involves leading machine learning engineering efforts within a research context, focusing on scaling and optimising AI models for high-fidelity physics and engineering simulations. The engineer will bridge research and production by transforming prototypes into robust, distributed systems, working closely with scientists and guiding junior team members. Key responsibilities include defining technical strategy, building scalable ML infrastructure, and mentoring within a collaborative, interdisciplinary team.

PhysicsX London, United Kingdom

On-site Permanent

Machine Learning Software Engineer, Research

This role involves working closely with research scientists and simulation engineers to build and optimize machine learning models for real-world physics and engineering problems. You will design, implement, and scale models using distributed training architectures and cloud services, while also mentoring colleagues and translating research into reusable libraries and products.

PhysicsX London, United Kingdom

On-site Permanent

Data Scientist - Defence & Security

This role involves working on cutting-edge machine learning and GenAI solutions, deploying LLMs and ML models in secure government and defence environments. You will lead technical delivery, design and optimise pipelines, and mentor junior engineers within a specialist team.

eFinancialCareers London, United Kingdom £75,000 pa

On-site Permanent Clearance Required

Software Engineer, Platform Systems

About the TeamThe Platform Systems team at OpenAI operates at the intersection of cutting-edge AI and large-scale distributed systems. We build the engineering and research infrastructure required to train OpenAI’s flagship models on some of the world’s largest, custom-built supercomputers.Our...

OpenAI London, United Kingdom

Permanent

Senior Security Engineer, London

As a Senior Security Engineer, you will play a crucial role in architecting and managing the security of Isomorphic Labs' AI-based platform and HPC infrastructure. You will work closely with DevOps, SRE, and other teams to ensure robust security practices, including threat modeling, incident response, and compliance automation.

Isomorphic Labs United Kingdom

Hybrid Permanent

Senior Data Scientist

As a Senior Data Scientist, you will lead the delivery of advanced data science capabilities, working on innovative projects to help customers unlock value from complex datasets. You will mentor colleagues, shape the future of the data science team, and collaborate closely with project leads and customers to develop and implement cutting-edge solutions.

MASS Little Paxton, Cambridgeshire, United Kingdom £45,000 – £65,000 pa

On-site Permanent Clearance Required

Snr/Principal Machine Learning Scientist – Generative Modelling

This role involves designing and implementing generative models to understand and control cellular decision-making, using cutting-edge multiomic and interventional datasets. You will collaborate with experimental teams to validate computational hypotheses and contribute to high-impact publications, pushing the boundaries of generative modelling in complex biological systems.

Relation Therapeutics London, United Kingdom

On-site Permanent

Data Scientist – Computational Genomics, 12-month

This role involves applying and developing machine learning and statistical models to analyse large-scale genomics and multi-omics datasets, with a focus on target identification and validation in drug discovery. The Data Scientist will work at the intersection of genetics, machine learning, and functional biology, integrating human genetics data with single-cell and biobank resources to generate actionable biological insights. Collaboration with experimental and computational teams is central to validating hypotheses and guiding therapeutic development.

Relation Therapeutics London, United Kingdom

On-site Permanent