Small Molecules Platform ASTL Lead

Site Name:UK - Hertfordshire - Ware
Posted Date:Aug 28 2024

Director, Small Molecule Platform ASTL Lead

This role will preferably be based in GSK Ware, UK.

The Global Supply Chain Manufacturing Science and Technology (MSAT) organization is a network-focused function which provides strategic platform direction and technical and operational support to ensure that GSK Global Supply Chain network, site goals and objectives are achieved, with determined strategy executed.

MSAT is the keeper of the body of manufacturing process knowledge, creates the instruction set and ensures manufacturing operations stay aligned with the registered process, with the primary objective being to ensure manufacturing processes are in control, compliant, performant & cost-efficient and remain state of the art.

In this truly exciting role as a Small Molecule Platform ASTL(Analytical Science &Technology) Lead, you will be responsible for the delivery of business-critical projects by supporting all the analytical aspects related to the late phase of the product lifecycle (PPQ/Post Commercial) for key GSK products. It also defines the strategy and provides leadership to implement Product control strategies, technology transfers, provides technical and analytical support across the product lifecycle, while implementing new products and new modalities for commercial products and product-related strategic programs within the GSK GCS.

The successful candidate will lead a team of 5 direct reports possess a high degree of emotional intelligence and be able to demonstrate their stakeholder influence and management skills.

Are you ready to shape the future of healthcare?

In this role you will

• Leading, developing and coaching a team of Analytical Science & technology leaders accountable for GSK products analytical life cycle management.
• Being accountable for the E2E life-cycle Product control strategy, providing expertise for product critical quality attribute assessment, specifications, comparability criteria setting.
• Leading cross-functional, cross-site teams, covering all analytical aspects in the frame of GSK strategic products and projects and bringing the Products specific analytical and stability expertise to multi-disciplinary technical teams and Governance bodies.
• Coordinating complex analytical investigations making use of scientific principles and professional practices to solve problems in creative and practical ways and driving implementation of appropriate corrective and preventative actions.
• Independently reviewing existing process and analytical development and production data; supporting design of experiments; recommending changes and improvements to the control strategy.
• Providing scientific support and mentorship in the development, scale-up, optimization and operation of methods for the production, purification and testing of new process formulas, technologies, and products.

CLOSING DATE for applications: 11th September 2024

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application, you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process.

Why you?

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• BSc, MSc or PhD in a related scientific discipline such as Biochemistry, chemistry, pharmacy, or biology - preferably Chartered / Professional Qualification
• Experience in Analytical Technologies
• Experience in development, qualification and validation of analytical methods
• Experience of New Product Introduction and Manufacturing Operations
• Experience of working with regulatory agencies in the frame of IND/BLA for (Bio)Therapeutics or vaccines and to GMP standards
• Experience in matrix leadership and project management

• Preferred Qualifications & Skills:

• Ph.D. or MS degree with significant experience in Bio(Pharma) Industry
• Experienced in technology transfer, with an understanding of the product development process and manufacturing
• Knowledge of current and emerging Regulatory Strategies (Quality by Design, GMP for 21st century, ICH Q7, Q8, Q9, Q10) and Product Lifecycle Management.
• Track record of improving products, processes and trouble-shooting, execution of technical activities including experimentation and analytical methods validation activities
• Excellent problem solver and ability to think and work creatively. Demonstrated experience leading technical aspects of root cause analysis investigations
• Demonstrated experience in the (Bio)Pharmaceutical industry in leading the Technical aspects of Product Lifecycle Management.

• Ability to display a clear willingness to listen to others and demonstrate good interpersonal skills and works collaboratively in an effective manner to achieve objectives.

We make and supply medicines and vaccines all around the globe and our teams own every production stage, from creating quality products at our manufacturing sites to designing effective supply forecasting and regulatory inspections; all powered by digital, data and analytics. We operate at impressive scale, producing over 2.3 billion packs of medicines and doses of vaccines in 2023.

We continue to modernise, so we can launch even more new products at speed whilst continuing to deliver across our entire portfolio through our relentless focus on quality, safety, and service. The way we work will change. For some, the shift in technology and products will be revolutionary. Our R&D pipeline demands a new kind of supply chain, and we need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.

If you are interested in joining us, find out more:

Annual Report 202 3

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or .

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.