Artificial Intelligence Jobs in Manchester

Hadean · London

Lead a new AI-powered defence product team, line-managing AI/ML, simulation, infrastructure and web engineers while staying hands-on in TypeScript, React and Node. You own delivery end-to-end, hiring and people development, partnering with Product and technical leads, with hybrid working one day a week in Shoreditch.

The University of Manchester · Manchester · £48,337 – £59,390 pa

Develops and applies machine-learning and AI methods to protein engineering and enzyme design, analysing large biological, chemical and experimental datasets and building predictive models and computational tools. Works within an interdisciplinary group spanning the Manchester Institute of Biotechnology and Department of Chemistry, providing ML and data-science expertise, training and support to postdocs and students, and contributing to publications and funding bids.

The University of Manchester · Manchester · £21,805 pa

A 3.5-year PhD developing an AI-enabled digital twin framework to support circular retrofit decision-making in ageing public buildings such as schools and healthcare facilities. The research integrates building condition data, asset records, material inventories and lifecycle information to evaluate component condition, estimate remaining service potential and prioritise reuse over replacement, validated through public-building case studies.

The Portfolio Group · Manchester

Set the AI vision and roadmap while staying hands-on, architecting and deploying machine learning and generative AI solutions into production. Work spans RAG, LLMs, vector search and knowledge graphs, plus building a cross-functional team and establishing AI governance. Based fully on-site in Manchester, reporting into senior leadership.

Searchability · Manchester · £90,000 – £100,000 pa

Designs, builds and optimises production-grade AI solutions focused on RAG, LLMs and agentic workflows. Works with AI Platform Engineers to develop RAG pipelines, improve retrieval, implement fine-tuning and establish evaluation frameworks, while contributing to technical decisions, code reviews and mentoring.

83zero · London · £65,000 – £80,000 pa

Builds GenAI proof-of-concepts and production systems for clients, using RAG, intelligent agents and LLM frameworks alongside full stack development. Works across Python/FastAPI or TypeScript backends, React frontends, cloud infrastructure and container orchestration, while engaging senior client stakeholders on GenAI strategy. Requires Security Check clearance.

83zero · Manchester · £60,000 – £80,000 pa

Builds GenAI proof-of-concepts and production systems for clients, using RAG, intelligent agents and LLM frameworks such as LangChain and CrewAI. The full stack role spans Python/FastAPI or TypeScript backends, React frontends, plus AWS or Azure deployment with Docker, Kubernetes and Terraform. Working alongside senior client stakeholders to turn business problems into scalable, secure technical solutions.

Carrington Recruitment Solutions · Liverpool · £75,000 – £85,000 pa

Hands-on lead role guiding a small development team across a portfolio of applications while shaping delivery and engineering standards. You'll work with C#, .NET, Python, Azure PaaS and React, collaborating with Product and Architecture, with an AI edge using GenAI tools like Copilot, ChatGPT or Claude. Mainly remote with occasional travel to Leeds and other offices.

Carrington Recruitment Solutions · Manchester · £80,000 – £90,000 pa

Hands-on full stack lead role guiding a small development team across a portfolio of applications, setting engineering standards and shaping delivery. Works with C#, .NET, Python, Azure PaaS, SharePoint and React, collaborating with Product and Architecture, with an AI-native edge using GenAI tooling. Mainly remote with occasional Manchester office visits.

Amazon · London

Lead end-to-end delivery of complex AI/ML engagements for enterprise customers, from strategic planning through pre-production deployment and optimisation. Architect solutions on AWS services with a focus on Generative AI using Amazon Bedrock and SageMaker, while mentoring junior consultants and supporting pre-sales scoping. Based in AWS UK offices when not at customer sites.

BIMM University · Hove · £39,000 – £45,000 pa

Designs, builds and improves digital products, web applications and AI-enabled workflows that support students and staff across a multi-campus university. Works within Digital, AI and Platform Services on integrations, APIs and automation, moving AI prototypes into production while embedding security, accessibility and privacy. Uses C#/.NET, TypeScript/JavaScript and product insight to drive continuous improvement.