Job description
Site Name:UK - Hertfordshire - Stevenage
Posted Date:Nov 19 2024

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

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Single Cell Analytical Scientific Investigator

We are seeking motivated analytical scientists with single cell spatial omics expertise to join our dynamic and expanding Respiratory and Immunology Translational Research and work closely with stakeholders across GSK R&D including Human Genetics and Genomics, Omics Technologies and AIML.

You will focus on the processing, analysis and integration of diverse and complex single cell spatial omics data to impact translation of our targets to the clinic. In addition, you will be experienced in the development and optimisation of associated laboratory technologies. Your work will have application across our pipeline, from multi-omic characterisation of disease endophenotypes to biomarker discovery, efficacy evaluation and patient stratification. Ultimately you will contribute to the Cell Atlas approach in Drug Discovery and Development to accelerate projects in the portfolio with translational confidence.

The successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance Drug Discovery and Clinical Development.Additionally, you will be encouraged and supported to continue to build your scientific profile through presentations, development programmes and peer-reviewed publications.

We are looking for this role to be based at Stevenage site only.

In this role you will...

• Deliver innovative analysis and integration of single cell and spatial omics data with tangible impact on the GSK pipeline.
• Develop and optimise single cell and spatial omics technologies in the lab.
• Data processing (low and high level), management, data transfer, data governance, data stewardship.
• Data curation, including identification, cataloguing and harmonisation of data.
• Work collaboratively alongside computational biologists in the Human Genetics and Genomics Translational Omics team and within cross-functional project teams with GSK scientists and external collaborators, with an emphasis on immunology in the context of hepatology, respiratory, renal or CNS diseases.
• Effectively communicate analysis findings, with expert translational interpretation, to project and disease area teams.

​Why you? 

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• PhD or BSc and equivalent experience in computational biology, AIML, data science, computational sciences, bioinformatics or biomedical/biological sciences.
• Experience of managing data workflows, including data curation from multiple sources.
• Experience in a programming language (such as R or Python) for complex data analysis and a good working knowledge of common bioinformatics databases, resources and tools.
• Experience of working directly with samples or processing samples through omics technologies, including expertise in the development and optimisation of single cell and spatial omics technologies.
• Solid understanding of analytical and statistical methods relevant to large scale analysis of biological data sets.
• Ability to work effectively and flexibly across multidisciplinary teams in a matrix environment.

Preferred Experience:

If you have the following characteristics, it would be a plus:

• Demonstrated experience in the analysis and integration of multi-omics data at the single cell level, including spatial distribution of gene expression within tissue or cell samples.
• Experience in the analysis and integration of single cell genomic data linked to clinical phenotypes with multiple data types for reverse translation and/or patient stratification.
• Experience in analysing and integrating data sets related to immunology in the context of hepatology, respiratory, renal or CNS diseases.
• Skills to collect, integrate, mine and analyse complex biological data and translate them into testable hypotheses.
• Experience in communicating complex scientific concepts to diverse audiences.

Closing Date for Applications: Monday 2nd December 2024

Please take a copy of the Job Description, as this will not be available post closure of the advert.
 When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

GSK R&D

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery.  We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together.

Find out more:

Our approach to R&D.   

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

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