You will be supporting the progression of therapeutic molecules at early stages of research and generating translational in vitro assays; to test novel therapeutics, investigate mechanisms of action and to identify novel therapeutic axes.
What youll do
- Deliver high quality data with defined timeframes.
- Ability to troubleshoot issues and identify and develop solutions to methodological challenges.
- Maintain operational functionality of equipment and ensure good laboratory housekeeping.
- Strong teamwork skills, provide help and if required training to colleagues.
- Present data with clarity and confidence to team members and wider project groups
- Be a key source of information relating to field of expertise, liaising with internal and external stakeholders to stay abreast of new advances in technologies and techniques.
- Maintain Health Safety awareness to ensure safe working practices.
Interested?For this role were looking for the followingeducation, experience and skills
- Extensive experience of tissue processing, working with FFPE and frozen tissues, microtome and cryotome sectioning from a wide range of human sample types.
- Extensive experience of immunofluorescence (IF) single/multi plex staining
- Experience with special stains, immunohistochemistry (IHC), and RNAscope assays
- Experience with automated tissue staining platforms.
- Ability to validate and optimize novel antibodies for immunohistochemistry
- Expertise in image acquisition of tissue sections and subsequent image analysis using commercially available platforms/software.
- Handling human tissue and deep understanding of the use of human tissue in the UK (HTA regulations) will be well received.
- Expertise in FAIR and ALCOA data integrity practices
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