190 jobs
Isomorphic Labs London
Drive DMPK strategy across drug discovery projects, designing screening cascades and mechanistic experiments with an AI-first approach. Integrate DMPK, PD and toxicology data to predict human dose and safety windows, and author regulatory documents. Work closely with AI/ML drug design platform teams in a hybrid London setting.
Isomorphic Labs Lausanne, Switzerland
Architect and secure an AI-first drug discovery platform, reporting to the CISO. You will build AI-specific risk frameworks, protect model artifacts, deploy LLM and agentic guardrails, and lead AI security incident response across distributed training and inference infrastructure.
Synthesia London
Own the end-to-end Interactive Avatar API, taking it from closed beta to general availability. Define the developer-facing surface (SDK, integration patterns, docs), real-time experience quality, and the commercial model, working closely with engineering, research, and design partners.
Synthesia Seattle, United States
First Developer Advocate for an AI video platform's API, responsible for writing tutorials and blog posts, building sample apps and starter kits, and producing video walkthroughs and livestreams. Represents the company at conferences, meetups and hackathons while channelling developer feedback back to Product and Engineering, and growing community channels like Discord and a developer newsletter.
PhysicsX New York, United States US$240,000 – US$300,000 pa
Leads regional deployment engineering for a physics AI platform, owning end-to-end success of customer-owned infrastructure deployments. Acts as primary technical contact for CIOs and CTOs, overseeing Kubernetes-based platform rollouts, security reviews, and version upgrades while hiring and growing a team of deployment engineers.
PhysicsX New York, United States US$150,000 – US$250,000 pa
Builds and deploys customer-facing applications on top of physics AI models, working directly with clients, data scientists and ML engineers. Involves full-stack work: FastAPI REST APIs and Python microservices, plus cloud deployment with Helm, Kubernetes, Terraform and AWS/Azure. Expect on-site travel to customer sites for 3-4 weeks per quarter.
Entrust London
Owns a core area of the document verification platform, setting strategy and roadmap for identity document checks used in onboarding and account opening. Works with Engineering, AI/ML, Data Science, Design, Growth and Compliance to improve verification accuracy, conversion, operational efficiency and fraud prevention, using experimentation and analytics.
University of Southampton Southampton £41,064 – £45,064 pa
Embed physics-informed generative AI tools into a marine vessel concept, generation and evaluation platform as part of a Knowledge Transfer Partnership between Compute Maritime Ltd and the University of Southampton. Develop and validate fast physics-informed models for ship resistance, propulsion and energy efficiency using CFD and benchmark data, and integrate multidisciplinary optimisation methods into the NeuralShipper platform.
OpenAI London
Lead and grow a London-based engineering team building real-time safety and oversight systems for AI agents, including the Auto-review permission-boundary model. The role blends hands-on technical work—shaping architecture, reviewing designs, debugging, and coding—with hiring, coaching, and setting the operating cadence. It is highly cross-functional, partnering with alignment researchers, product, security, and infrastructure teams.
Wayve London
Builds and evolves the data pipeline and orchestration platform behind Wayve's autonomous driving data, revamping the existing Harness system and creating a new DAG-based workflow platform. Works with Python, Airflow/Dagster/Flyte, Ray or Spark and Kubernetes to run hundreds of parallel pipeline steps, batch inference and evaluations reliably at scale.
Thought Machine Lisbon, Portugal
Full-stack role building end-to-end features across web applications and backend services, with React and TypeScript on the front end and REST APIs behind. Engineers own requirements from design and task breakdown through testing, debugging and production, working in a cross-functional team for banking clients.
Luminance London
Sits at the intersection of product, customers and market, working with blue-chip clients to maximise value from legal-grade AI technology and shape product innovation for a global customer base. Also acts as a company ambassador, speaking at industry conferences and partnering strategically with the leadership team.
Relation Therapeutics London
Develops and benchmarks machine learning models for DNA sequence, regulatory elements and genetic variation, including variant effect prediction and representation learning. Integrates sequence-derived representations with transcriptomic, epigenomic and perturbational data to uncover disease mechanisms and support target prioritisation, working within the interdisciplinary Rosalind team.
Thought Machine Lisbon, Portugal
Owns complex, ambiguous technical challenges end-to-end, shaping long-term platform architecture and company-wide engineering standards. Drives adoption of AI tooling, leads technical interviews, and mentors senior engineers while acting as a link between leadership and engineering teams. Based in the Lisbon office, requiring three days a week onsite.
OpenAI London
Lead a team of senior Applied AI Architects acting as the technical "CTO of the book of business" for OpenAI's largest enterprise customers across North EMEA. Own technical account strategy, resource allocation and paths to production across ChatGPT Enterprise, the API, Codex and agentic solutions, while coaching the team and serving as an executive technical sponsor.
