Jobs in Cambridge

Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA

This role involves leading translational biology strategies in oncology and immunology, bridging AI-driven drug design with experimental validation. You will design in vivo pharmacology studies, develop biomarker strategies, and manage CRO partnerships to generate robust data for clinical translation. The position plays a key role in advancing drug candidates from discovery through to clinical development by integrating biological insights with machine learning predictions.

Isomorphic Labs England

Hybrid Permanent

Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA

Lead or contribute to drug discovery projects by integrating medicinal chemistry expertise with AI-driven platforms. Collaborate closely with machine learning teams to refine predictive models and drive programs from hit identification to candidate selection. Play a key role in shaping next-generation drug design through innovation in structure-based and fragment-based approaches, while mentoring teams and managing external research partners.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Senior Security Researcher - Agent Workflow

This role involves researching and prototyping agentic AI workflows within cybersecurity, exploring how autonomous systems can enhance threat detection and response across Darktrace’s platform. You'll collaborate with product, engineering, and ML teams to translate novel AI concepts into functional prototypes, while maintaining deep expertise in both AI advancements and security applications. The position emphasizes innovation, cross-functional coordination, and applied research in a real-world cyber defense context.

Darktrace London, UB8 1LQ, United Kingdom

Hybrid Permanent

Machine Learning Integration Engineer

This role involves integrating and optimizing machine learning models into Darktrace’s cybersecurity platform, focusing on improving runtime, scalability, and effectiveness against unknown threats. You'll work closely with machine learning specialists and security researchers to prototype and deploy innovative AI solutions. The position emphasizes production-quality Python development, model acceleration, and performance optimization across diverse technology stacks.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Hybrid Permanent

Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA

This role involves leading drug discovery programs using AI-driven computational chemistry, either as a Program Lead or Computational Chemistry Lead. You'll shape Isomorphic Labs' AI platform by integrating cutting-edge machine learning into cheminformatics workflows, guide projects from hit identification to candidate selection, and collaborate across disciplines. The position emphasizes scientific leadership, technical innovation, and mentorship within a culture focused on transforming drug discovery through AI.

Isomorphic Labs Cambridge, United Kingdom

Hybrid Permanent

Associate Director, Clinical Program Management, Cambridge, MA

The Clinical Program Manager will lead the transition of internal drug programs from pre-IND stages into clinical trial execution, managing timelines, budgets, and cross-functional teams. This role involves close collaboration with AI/ML and data science teams, CROs, and global stakeholders to ensure efficient, high-probability clinical development. The position operates in a hybrid model, requiring in-office presence multiple days per week in Cambridge, MA.

Isomorphic Labs England

Hybrid Permanent

Medical Director, Clinical Development (Oncology), Cambridge, MA

Lead clinical development strategy for oncology programs, translating AI-driven insights into actionable trial designs and overseeing medical monitoring from discovery through to clinical proof-of-concept. Serve as the primary medical liaison with regulatory authorities, investigators, and cross-functional teams, ensuring scientific rigor, patient safety, and compliance with global standards.

Isomorphic Labs England

Hybrid Permanent

Director, Translational Medicine, Oncology, Cambridge, MA

Lead the development and execution of translational medicine strategies for oncology programs, integrating AI-driven insights to advance drug discovery from preclinical to clinical stages. Serve as a cancer biology expert, guiding biomarker and companion diagnostic development while collaborating across multidisciplinary teams. Shape clinical trial design and regulatory submissions with a focus on mechanism of action, drug resistance, and novel therapeutic combinations.

Isomorphic Labs Cambridge, United Kingdom

Senior C++ Software Engineer

Design and develop high-performance, low-latency C++ systems for cybersecurity applications, focusing on innovation, memory safety, and scalability. Work within a cross-functional R&D team to build secure, production-grade native tooling that defends against unknown threats. Utilise modern C++ (C++17/20+), systems programming, and performance optimisation in Linux and cloud environments.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Hybrid Permanent

Senior Software Engineer (C++ & Swift)

You will develop and maintain the macOS codebase using modern C++ and Swift, contributing to the design and implementation of innovative cybersecurity solutions. The role involves rapid prototyping, structured development of platforms, and mentoring team members. You will work closely with cross-functional teams, participate in code reviews, and help advance Darktrace’s AI-driven methodology for detecting and responding to unknown cyber threats.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Specialist Software Engineer

This role involves leading high-impact technical projects within Darktrace’s R&D team in Cambridge, focusing on advancing AI-driven cybersecurity solutions. You’ll provide strategic technical direction, mentor engineers, and innovate in detecting and responding to novel cyber threats. The position blends rapid prototyping with structured development, requiring deep expertise in software architecture, security, and distributed systems.

Darktrace United Kingdom

Specialist Software Engineer

This role involves leading high-impact technical projects within Darktrace’s R&D team, focusing on advancing AI-driven cybersecurity solutions to counter novel threats. The engineer will drive innovation through rapid prototyping, mentor team members, and shape strategic technical direction. Collaboration with cross-functional teams and executive communication are key aspects of the position.

Darktrace

Threat Research Analyst

The role involves in-depth analysis of cyber threats, malware, and adversary TTPs using data science and analytical techniques. You'll proactively hunt for emerging threats, develop detection methodologies, produce threat intelligence reports, and collaborate with research and product teams. The position emphasizes turning complex data into actionable insights and contributing to public-facing research and conferences.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Product Manager - NDR

This role involves shaping the Network Detection and Response (NDR) product within Darktrace’s AI-driven cybersecurity platform. The Product Manager will bridge customer needs, technical development, and go-to-market strategy, working closely with R&D, marketing, and sales teams. Key responsibilities include defining product direction, validating features, and ensuring effective internal and external communication of product capabilities.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Hybrid Permanent

Product Manager - NDR

This role involves shaping the direction of Darktrace's Network Detection and Response (NDR) product by aligning customer needs with technical development. The Product Manager will work closely with R&D, marketing, and go-to-market teams to prioritise features, ensure effective product messaging, and support customer adoption. A strong understanding of cybersecurity, particularly in network security and real-world NDR deployment, is essential for success in this position.

Darktrace London, UB8 1LQ, United Kingdom

Hybrid Permanent