ociate Director Non-Clinical Pharmacokinetics Pharmacodynamics

Lifelancer

Slough

1 year ago

Applications closed

We are looking for a an enthusiastic communicative matrixteam operational individual with Preclinical Pharmacokinetics and pharmacodynamics (PKPD) experience to join us at our Slough site in Berkshire UK.
About the roleYou will be an integral part of the team to drive strategy and support projects by exploring PK/PD relationships in preclinical models to help understand the dose and schedule requirements for therapeutic interventions.

What youll do

Develop and drive the nonclinical PKPD strategy for projects. Communicate this effectively ensuring implementation in projects.
Ensure translation from in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients.
Initiate and engage in multifunctional collaborations to facilitate the advancement of drug candidates and build a thorough knowledge of drug pharmacology and PKPD leading to quantitative translation to the clinic
Build PKPD models to allow hypothesis testing and inform decisionmaking.
Provide scientific and technical input expertise and leadership to Nonclinical PKPD group project teams and the department.
Work in collaborations with external partners academic institutions CROs and consultants as required.
Maintain an awareness of new / emerging techniques and tools relevant to the field.
Represent the interests of QCP internally and externally in matters relevant to mechanistic PKPD and contribute to enhancing the scientific reputation of NonClinical PKPD
As required contribute to Due Diligence of external project product and technology opportunities
Provide required support and input into regulatory study protocols reports and summaries and regulatory submission documents.

Interested For this role were looking for the following education experience and skills

PhD in relevant discipline (pharmacology bio/engineering pharmacokinetics/pharmacodynamics etc.)
Good understanding of pharmacology and the pharmacology processes related to disease and drug mechanisms
Expertise and proven application of PKPD methods and concepts in support of drug discovery and development. Systems modelling experience would be advantageous
Demonstrated experience in developing and executing effective nonclinical PKPD strategies from early discovery through to clinic
Innovative selfmotivated teamoriented scientist with good written and verbal communication skills able to handle several projects at any given time to work successfully in teams and to communicate clearly to a variety of audiences
Demonstrated leadership skills in a matrix environment capable of working effectively in teams and influencing relevant stakeholders
Experience working within a matrix environment with a wide range of internal stakeholders including NonClinical Safety Bioanalysis Clinical Pharmacology and Translational Medicine.
Record of publications and other external scientific contributions relevant to PKPD
Experience in using modelling and simulation packages such as Phoenix Berkeley Madonna Monolix R

Lifelancer () is a talenthiring platform in Life Sciences Pharma and IT. The platform connects talent with opportunities in pharma biotech health sciences healthtech data science and IT domains.

Please use the below Lifelancer link for job application and quicker response.

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