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Associate Director Senior Principal Scientist in PK Science

FCRS = GB016
London
2 months ago
Applications closed

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Band

Level 5


Job Description Summary

50 projects are being supported in the Immunology Therapeutic Area within the PK Sciences department. We provide PK and PK/PD strategies from early discovery all the way through to registration and beyond. More than half of this portfolio represents biologics projects spanning from classical monoclonal antibodies to complex biologics constructs and extending to Tcell therapies including CART cell modalities and Tcell engagers. Since our portfolio is growing our Team likes to expand by adding an experienced Team member who will drive our biologics projects.

Your Responsibilities:
Your responsibilities include but are not limited to:
Independently represents PK Sciences as a core member of discovery translational and global project teams and leads a PKS subteam to define PKS strategy for compound progression and development.
Analyze and interpret PK/PD/IG data generated during discovery early and full development; present results to the program.
Proactively identifies potential project hurdles provides solutions and contributes to contingency plans.
Independently authors and contributes to key clinical and regulatory documents including but not limited to: clinical study protocols clinical study reports modeling reports investigator brochures IND / IMPDs and NDAs within agreed timelines and meeting all regulatory requirements.
Publishes internally or externally as main contributor to enhance Novartis and PK Sciences visibility.


Please note this is a hybrid role there is a requirement of a minimum of three days on site in the London office per week or twelve days a month.

We are unable to offer permit sponsorship for this role.


Job Description

  • What youll bring to the role:
    Ability to work in and adopt to a changing scientific & regulatory environment

    A strong team player demonstrating excellent communication skills and with experience in leading crossfunctional teams

    A curious mind and a genuine interest in collaborative interactions across disciplines

    PhD MD or PharmD in life sciences/healthcare with a focus on biologics therapies

    Credible background and indepth expertise in clinical pharmacology with significant 5 years) drug development experience with the focus on biological drug candidates (all modalities)

    Uptodate background on stateoftheart scientific and regulatory aspects of biologics drug development
    Experience with standard PK analysis software (Phoenix) and understanding of applications of M&S techniques

Why NovartisOur purpose is to reimagine medicine to improve and extend peoples lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here:receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook.

Accessibility & Accommodation :Novartis is committed to working with and providing reasonable accommodation to all individuals. If because of a medical condition or disability you need a reasonable accommodation for any part of the recruitment process or in order to receive more detailed information about the essential functions of a position please send an email to and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Join our Novartis Network:If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities join the Novartis Network here:Desired

Chemistry Clinical Pharmacology Clinical Research Clinical Study Reports Clinical Trials Data Entry Drug Discovery Due Diligence Electronic Components Gene Therapy Lifesciences Medical Research Microsoft Office Modeling And Simulation Patient Care Physics Translational Medicine Waterfall Model


Required Experience:

Director


Key Skills
Machine Learning,Python,Data Science,AI,R,Research Experience,Sensors,Drug Discovery,Research & Development,Natural Language Processing,Data Analysis Skills,Toxicology Experience
Employment Type :Full-Time
Experience:years
Vacancy:1

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