Artificial Intelligence Jobs in Southampton

• Southampton
• £37,369 – £45,641 pa
• Mid-level
• Contract · Part time

A part-time research post developing and commercialising AI-enabled healthcare tools, combining hands-on software engineering and system architecture with product development and evaluation. The role involves building, testing and deploying software with large language model and agentic AI capabilities, connecting diverse datasets, research algorithms and external services, while supporting commercial partnerships, customer discovery, business models and pilot delivery.

• Southampton
• Hybrid
• £41,064 – £45,064 pa
• Contract

Embed physics-informed generative AI tools into a marine vessel concept, generation and evaluation platform as part of a Knowledge Transfer Partnership between Compute Maritime Ltd and the University of Southampton. Develop and validate fast physics-informed models for ship resistance, propulsion and energy efficiency using CFD and benchmark data, and integrate multidisciplinary optimisation methods into the NeuralShipper platform.

PyTorch · TensorFlow · JAX +2

• Southampton
• Hybrid
• £45,900 pa
• Lead
• Permanent

Lead the Maritime Innovation Hub's work on digitalisation, AI, data, connected technologies and autonomous surface ships. You will horizon-scan, build industry and academic networks, produce guidance, and support policy and regulatory colleagues while helping innovators navigate the maritime regulatory regime. The role is outward-facing and international, feeding into the IMO Digitalisation Strategy.

• Southampton
• On-site
• £40,000 – £50,000 pa
• Mid-level

Build and maintain features end-to-end, from UI through APIs, databases and deployment, working across the full stack rather than specialising in one layer. The team takes ownership of features from concept to deployment and actively uses AI-assisted tools like Claude, Copilot and Cursor for coding, testing and documentation.

Claude · GitHub · Copilot +3

• Eastleigh
• On-site
• £50,000 – £70,000 pa
• Senior

Full-stack role building and maintaining features end-to-end, from UI through APIs, databases and deployment, working across frontend, backend, data and web rather than specialising. Developers own features from concept to deployment and use AI-assisted tools such as Claude, Copilot or Cursor daily for coding, testing and documentation.

React · Vue · Svelte +8

• Southampton
• On-site
• £46,970 – £49,798 pa
• Senior · manages people
• Contract

Lead a translational research project extracting structured clinical findings from electronic health records using open-source large language models, harmonising them to ontologies such as HPO, SNOMED CT and ICD-10. Develop reproducible LLM-based pipelines on high-performance computing, integrate clinical and genomic data for autoimmune disease diagnostics, and manage early career researchers within a multidisciplinary team.

IRIDIS · HPO · SNOMED CT +6

• Southampton
• Hybrid · 2–3 days in office
• £65,000 – £75,000 pa
• Senior

Build cloud applications, customer portals, APIs and integrations that turn complex data into useful products, while developing AI capabilities such as document intelligence, semantic search, RAG and intelligent agents. Use tools like Claude Code and Codex, shape architecture and engineering practices, and work directly with users and domain specialists in a hybrid team near Eastleigh.

Azure · PostgreSQL · Claude Code +4