Artificial Intelligence Jobs in Newcastle

• Newcastle upon Tyne
• £37,369 – £51,258 pa
• Senior
• Contract

Manage the experimental delivery of an AI- and bioinformatics-augmented, high-throughput platform for discovering and engineering PET-depolymerising enzymes. Combines synthetic biology, enzyme engineering and bioinformatics to improve PETase, MHETase/BHETase and PET-binding modules through rapid Design-Build-Test-Learn cycles, working with ICOS, EBIC and international collaborators in Argentina.

PETase · MHETase · BHETase

• Newcastle upon Tyne
• Hybrid · 3 days in office
• £70,000 – £80,000 pa
• Senior

Senior technical lead in a shared-service AI and automation team, designing large-scale automation, Infrastructure as Code and domain-specific AI agents across Azure and OCI. Hands-on with Terraform/Bicep, CI/CD, scripting and LLM-assisted tooling, while mentoring engineers and driving AI-first, automation-first ways of working.

Azure · Oracle Cloud Infrastructure · Terraform +7

• London
• Hybrid · 2 days in office
• £65,000 – £80,000 pa
• Senior
• Permanent

Builds GenAI proof-of-concepts and production systems for clients, using RAG, intelligent agents and LLM frameworks alongside full stack development. Works across Python/FastAPI or TypeScript backends, React frontends, cloud infrastructure and container orchestration, while engaging senior client stakeholders on GenAI strategy. Requires Security Check clearance.

AWS · Azure · Docker +7

• Manchester
• Hybrid · 2 days in office
• £60,000 – £80,000 pa
• Senior
• Permanent

Builds GenAI proof-of-concepts and production systems for clients, using RAG, intelligent agents and LLM frameworks such as LangChain and CrewAI. The full stack role spans Python/FastAPI or TypeScript backends, React frontends, plus AWS or Azure deployment with Docker, Kubernetes and Terraform. Working alongside senior client stakeholders to turn business problems into scalable, secure technical solutions.

AWS · Azure · Docker +7

• Gateshead
• £25,900 pa
• Junior

Join an educational software support company to help build an AI Agent, working across data preprocessing, exploratory analysis, model fine-tuning and implementation of machine learning algorithms. Collaborate with cross-functional teams to define requirements and deliver scalable solutions while keeping up with the latest AI advancements. Aimed at early-career candidates with no prior experience required.

• South Shields
• £25,900 pa
• Junior

An early-career role building an AI Agent for an educational software support company, covering data preprocessing, exploratory analysis, model fine-tuning and implementing machine learning algorithms. The position works with cross-functional teams to define requirements and deliver scalable solutions, and is aimed at someone new to the industry with no prior experience required.

• Hungerford
• Hybrid · 3 days in office
• £70,000 – £80,000 pa
• Senior

Senior technical lead in a shared-service AI and automation team, designing large-scale automation, Infrastructure as Code and domain-specific AI agents across Azure and OCI. Hands-on with Terraform/Bicep, CI/CD, scripting and LLM-assisted tooling, while mentoring engineers and driving AI-first, automation-first ways of working to improve resilience and recovery times.

Azure · Oracle Cloud Infrastructure · Terraform +7

• Gateshead
• Remote
• £75,000 – £85,000 pa
• Lead · manages people

Hands-on lead role guiding a small development team across a portfolio of applications while setting engineering standards and shaping delivery. Tech stack spans C#, .NET, Python, React, SharePoint and Azure PaaS, with an AI-native edge using GenAI tools such as Copilot, ChatGPT or Claude. Mainly remote with occasional travel to Leeds and other offices.

Azure · Azure Functions · Azure Logic Apps +7