Latest High Performance Computing Jobs

Senior HPC Performance Engineer

In this role, you will analyze and optimize High Performance Computing (HPC) applications on NVIDIA's HPC servers and systems. You will work with a range of applications, from small benchmarks to large-scale distributed-memory systems, and provide insights to compiler and application engineering teams to enhance performance.

NVIDIA Germany

Remote Permanent

Senior HPC Performance Engineer

In this role, you will analyze and optimize High Performance Computing (HPC) applications on NVIDIA's HPC servers and systems. You will work with a range of applications, from small benchmarks to large-scale distributed-memory systems, and provide insights to compiler and application engineering teams to improve performance.

NVIDIA

Remote Permanent

Research Scientist - Material Modelling

This role involves developing and applying machine learning interatomic potentials (MLIPs) to model atomistic systems, using state-of-the-art frameworks and large-scale datasets in chemistry and materials science. The Research Scientist will design and run experiments, advance AI-driven simulation models, and collaborate across disciplines to translate research into production-ready pipelines. Work spans high-performance computing environments with a focus on real-world engineering impact across industries like aerospace, energy, and semiconductors.

PhysicsX London, United Kingdom

Hybrid Permanent

Senior Applied Engineer

Develop and scale physical foundation models by bridging research and engineering, transforming prototypes into robust, optimised AI-driven simulation systems. Work across scientific computing, distributed training, and cloud infrastructure to deliver high-impact solutions for real-world engineering problems in collaboration with research teams, customers, and partners.

PhysicsX United Kingdom

Hybrid Permanent

Snr Data Scientist, Computational Genomics/DNA Modelling

This role involves developing and applying machine learning models to understand the relationship between DNA sequence, regulatory elements, and disease biology. The data scientist will work on variant effect prediction, regulatory activity modelling, and integrating genomic data with transcriptomic and epigenomic datasets. Embedded in an interdisciplinary team, the role bridges computational research with experimental validation to advance target discovery and therapeutic development.

Relation Therapeutics London, United Kingdom

Hybrid Permanent

Senior Data Scientist - Single Cell & Spatial

This role involves developing and implementing computational workflows for integrating and analysing multi-omics data, designing statistical models, and collaborating with ML modellers and experimental teams to drive transformative insights in drug discovery. The position is embedded within the Single Cell and Spatial Omics team, offering a unique opportunity to work on cutting-edge projects with a focus on patient impact.

Relation Therapeutics London, United Kingdom

On-site Permanent

ML Runtime Engineer (Mid-Level and Senior)

This role involves developing and integrating high-performance ML runtimes for Fractile's novel AI accelerator hardware, focusing on inference server integrations with open-source frameworks like PyTorch, vLLM, and SGLang. Engineers will work closely with hardware and ML teams using a co-design approach to optimise performance. The position emphasizes low-level runtime development in Rust and deep collaboration across software and hardware layers.

Fractile Bristol, United Kingdom

Hybrid Permanent

ML Runtime Engineer (Mid-Level and Senior)

This role involves developing and integrating a high-performance Rust-based runtime for AI accelerators, focusing on inference server compatibility with open-source ML frameworks like PyTorch, vLLM, and SGLang. The engineer will work closely with hardware and ML teams using a co-design approach to optimize performance for large language models. Collaboration and ownership in a fast-paced, innovative environment are key aspects of the position.

Fractile London, United Kingdom

Hybrid Permanent

Senior Software Engineer

As a Senior Software Engineer at Medtronic, you'll develop high-performance embedded systems using modern C++ for next-generation intra-operative medical devices. You'll enhance real-time connectivity, computer vision, and decision support in surgical environments while ensuring software reliability, security, and compliance with medical-grade standards. The role involves close collaboration with multidisciplinary teams and contributing to both existing and emerging device platforms.

Medtronic London, United Kingdom £76,800 – £115,200 pa

Hybrid Permanent

Senior Program Manager – (Medical Device System)

At Medtronic you can begin a life-long career of exploration and innovation, while helping champion healthcare access and equity for all. You’ll lead with purpose, breaking down barriers to innovation in a more connected, compassionate world.A Day in the LifeMedtronic...

Medtronic London, United Kingdom

Junior Cloud Developer (Front End)

This role involves developing responsive front-end interfaces and cloud applications for fans, customers, and partners, with a focus on user experience and AI integration. You'll work alongside cloud architects to build and optimise digital experiences across desktop and mobile platforms. The position offers structured learning and growth within a high-performance sports technology environment.

Brighton & Hove Albion Football Club Bn159Fp, BN15 9FP, United Kingdom

On-site Permanent Clearance Required

Senior C++ Software Engineer

As a Senior C++ Software Engineer, you will work on the design, development, and optimization of high-performance, C++-driven systems. You will collaborate with a cross-functional team to deliver cutting-edge cybersecurity solutions, focusing on performance, scalability, and robustness.

Darktrace Cambridge, CB2 3BJ, United Kingdom

Hybrid Permanent

Senior Quantitative Developer / Research & Data Eng. - LONDON - UNITED KINGDOM

This role involves designing and enhancing real-time market data infrastructure, building scalable platforms for quantitative research, and developing simulation and backtesting environments. Engineers will also create research tooling, optimize performance-critical systems, and contribute to the architecture of next-generation trading and research infrastructure.

Park Lane Recruitment Ltd W1A1Aa, W1A 1AA, United Kingdom £250,000 – £600,000 pa

On-site Permanent

Embedded Automotive Platforms Software Engineer

This role involves developing embedded software platforms that interface with automotive hardware and Wayve’s AI driving models. The engineer will create abstractions and APIs to enable consistent deployment of autonomous vehicle software across different platforms, working on systems like Linux and QNX while minimizing platform-specific code. The position emphasizes performance, reliability, and close collaboration with hardware and software teams to advance scalable, production-ready AV technology.

Wayve London, United Kingdom

Hybrid Permanent

Software Engineer

This role involves developing advanced software solutions for complex systems using C++, with a focus on performance, functionality, and integration with engineering teams. The engineer will work across the full development lifecycle, including design, testing, and deployment, while contributing to technical documentation and code reviews. The position emphasizes high-performance, multi-threaded applications and offers exposure to domains such as computer vision and data analysis.

Tec Partners Recruitment Ltd Kelvedon, Essex, CO5 9AB, United Kingdom £55,000 – £75,000 pa

Hybrid Permanent