Latest Drug Discovery Jobs

Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA

This role involves designing and implementing biological screening cascades for drug discovery programs, with a focus on biophysical, biochemical, and cellular assays. The scientist will bridge computational predictions with experimental validation, working closely with AI/ML teams and CROs to advance oncology and immunology projects from early discovery to clinical development. Key responsibilities include guiding assay development, interpreting complex pharmacological data, and supporting lead optimization across multiple therapeutic areas.

Isomorphic Labs England

Hybrid Permanent

Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA

This role involves leading translational biology strategies in oncology and immunology, bridging AI-driven drug design with experimental validation. You will design in vivo pharmacology studies, develop biomarker strategies, and manage CRO partnerships to generate robust data for clinical translation. The position plays a key role in advancing drug candidates from discovery through to clinical development by integrating biological insights with machine learning predictions.

Isomorphic Labs England

Hybrid Permanent

Associate Director, Data Engineering

Lead the development and strategy of a unified data platform integrating wet and dry lab data to support drug discovery. Manage data engineering teams, optimize scientific compute pipelines using Nextflow and Seqera, and ensure FAIR data principles with strong governance and lineage. Operate in a highly interdisciplinary environment bridging biology, machine learning, and engineering.

Relation Therapeutics London, United Kingdom

On-site Permanent

Senior Scientist, Model Systems

The role involves developing and optimising robust mono- and co-culture models using human primary cells for high-throughput functional genomics studies in fibrotic disease. The scientist will automate perturbation screens, apply multimodal readouts including transcriptomics and proteomics, and work closely with cross-functional teams in a tech-driven biotech environment. Key responsibilities include assay development, imaging analysis, and integration of new technologies to advance target discovery.

Relation Therapeutics London, United Kingdom

On-site Permanent

Security Engineering Manager, London or Lausanne

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease.The future is coming. A future enabled and enriched by the incredible power of machine learning. A...

Isomorphic Labs United Kingdom

General Application - Register Your Interest

Isomorphic Labs is building advanced AI systems to accelerate drug discovery and transform the future of medicine. This is a general interest application for roles in software engineering, machine learning, computational chemistry, and technical project management within an interdisciplinary, research-driven environment. The role involves working at the intersection of AI and biology to develop predictive and generative models for rational drug design.

Isomorphic Labs United Kingdom

Hybrid Permanent

Clinical Program Manager, Cambridge, MA

This role involves leading the transition of internal drug programs from pre-IND stages into clinical trial execution, managing timelines, budgets, and cross-functional teams. The Clinical Program Manager will coordinate with clinical, preclinical, AI/ML, and data science teams to ensure efficient, AI-driven trial delivery. They will also oversee external vendors and CROs, ensuring successful delivery of key clinical milestones.

Isomorphic Labs England

Hybrid Permanent

Medical Director, Clinical Development (Oncology), Cambridge, MA

Lead clinical development strategy for oncology programs, translating AI-driven insights into actionable trial designs and overseeing medical monitoring from discovery through to clinical proof-of-concept. Serve as the primary medical liaison with regulatory authorities, investigators, and cross-functional teams, ensuring scientific rigor, patient safety, and compliance with global standards.

Isomorphic Labs England

Hybrid Permanent

Snr Scientist II / Principal Scientist, In Vivo Biology & Translational Science

This role involves leading in vivo pharmacology strategy and execution for multiple drug discovery projects, primarily through external CRO partnerships. The scientist will design and interpret studies across target engagement, PK/PD, and efficacy, translating biological data into actionable insights. Close collaboration with cross-functional teams ensures data drives go/no-go decisions in a fast-moving, interdisciplinary TechBio environment.

Relation Therapeutics London, United Kingdom

On-site Permanent

Data Scientist – Computational Genomics, 12-month

This role involves applying and developing machine learning and statistical models to analyse large-scale genomics, transcriptomics, and multi-omics datasets for target identification and validation in drug discovery. The Data Scientist will work at the intersection of computational genomics and ML, integrating human genetics data with functional omics to uncover disease mechanisms. Collaboration with experimental and machine learning teams is central, with an emphasis on reproducible workflows, hypothesis validation, and clear communication of insights.

Relation Therapeutics London, United Kingdom

On-site Permanent

Senior/Research Assistant, Genomics

This role involves end-to-end execution of single-cell RNA-seq and ATAC-seq workflows, generating high-quality sequencing libraries from perturbation screens. The candidate will work at the intersection of wet-lab genomics and automation, contributing to scalable, ML-ready multi-omic datasets. Close collaboration with computational and engineering teams ensures robust experimental design, metadata integration, and transition of manual protocols to automated platforms.

Relation Therapeutics London, United Kingdom

On-site Permanent

Snr Data Scientist, Computational Genomics/DNA Modelling

This role involves developing and applying machine learning models to understand the relationship between DNA sequence, regulatory elements, and disease biology. The data scientist will work on variant effect prediction, regulatory activity modelling, and integrating genomic data with transcriptomic and epigenomic datasets. Embedded in an interdisciplinary team, the role bridges computational research with experimental validation to advance target discovery and therapeutic development.

Relation Therapeutics London, United Kingdom

Hybrid Permanent

Machine Learning Scientist – Sequence Modelling

Develop and apply advanced machine learning models to DNA and genetic data to uncover associations between genetic variants and diseases. Collaborate with computational and experimental scientists to validate hypotheses and integrate ML into target discovery pipelines. Work on sequence modelling tasks such as variant interpretation, gene discovery, and regulatory mechanism analysis using large-scale genomic datasets.

Relation Therapeutics London, United Kingdom

Permanent

Senior Data Scientist - Computational Biology

This role involves applying advanced computational and statistical methods to single-cell, spatial, and multi-omics datasets to uncover disease mechanisms and inform drug discovery. The data scientist will collaborate closely with ML researchers, experimental biologists, and software engineers, translating complex biological data into actionable insights. Work includes developing analysis pipelines, validating computational hypotheses, and contributing to interdisciplinary research with direct patient impact.

Relation Therapeutics London, United Kingdom

On-site Permanent

Senior Data Scientist – Statistical Genetics

Leads statistical and population genomics analyses to support target identification and validation in drug discovery, using large-scale human genetics data and advanced methodologies. Integrates genetic insights with multi-omics datasets and collaborates across experimental, translational, and machine learning teams. Develops scalable, reproducible analysis pipelines and contributes to scientific communication and decision-making within a cross-functional biotech environment.

Relation Therapeutics London, United Kingdom

On-site Permanent